Astrocyte-derived small extracellular vesicles promote synapse formation via fibulin-2-mediated TGF-β signaling

Neuronal synapse formation is critical for brain development and depends on secreted factors from astrocytes. Here, we report that small extracellular vesicles (EVs) secreted from primary astrocytes, but not from neurons or C6 glioma cells, greatly enhance spine and synapse formation by primary cort...

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Detalles Bibliográficos
Autores principales: Patel, Mikin R., Weaver, Alissa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8002899/
https://www.ncbi.nlm.nih.gov/pubmed/33691102
http://dx.doi.org/10.1016/j.celrep.2021.108829

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8002899/
https://www.ncbi.nlm.nih.gov/pubmed/33691102
http://dx.doi.org/10.1016/j.celrep.2021.108829

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