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Astrocyte-derived small extracellular vesicles promote synapse formation via fibulin-2-mediated TGF-β signaling
Neuronal synapse formation is critical for brain development and depends on secreted factors from astrocytes. Here, we report that small extracellular vesicles (EVs) secreted from primary astrocytes, but not from neurons or C6 glioma cells, greatly enhance spine and synapse formation by primary cort...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8002899/ https://www.ncbi.nlm.nih.gov/pubmed/33691102 http://dx.doi.org/10.1016/j.celrep.2021.108829 |