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Glycine and N‐acetylcysteine (GlyNAC) supplementation in older adults improves glutathione deficiency, oxidative stress, mitochondrial dysfunction, inflammation, insulin resistance, endothelial dysfunction, genotoxicity, muscle strength, and cognition: Results of a pilot clinical trial

BACKGROUND: Oxidative stress (OxS) and mitochondrial dysfunction are implicated as causative factors for aging. Older adults (OAs) have an increased prevalence of elevated OxS, impaired mitochondrial fuel‐oxidation (MFO), elevated inflammation, endothelial dysfunction, insulin resistance, cognitive...

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Detalles Bibliográficos
Autores principales: Kumar, Premranjan, Liu, Chun, Hsu, Jean W., Chacko, Shaji, Minard, Charles, Jahoor, Farook, Sekhar, Rajagopal V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8002905/
https://www.ncbi.nlm.nih.gov/pubmed/33783984
http://dx.doi.org/10.1002/ctm2.372