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Allelic Expression Imbalance Analysis Identified YAP1 Amplification in p53- Dependent Osteosarcoma

SIMPLE SUMMARY: Osteosarcoma (OS) is a highly heterogenous cancer, making the identification of genetic driving factors difficult. Genetic factors, such as heritable mutations of Rb1 and TP53, are associated with an increased risk of OS. We previously generated pigs carrying a mutated TP53 gene, whi...

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Detalles Bibliográficos
Autores principales: Niu, Guanglin, Bak, Agnieszka, Nusselt, Melanie, Zhang, Yue, Pausch, Hubert, Flisikowska, Tatiana, Schnieke, Angelika E., Flisikowski, Krzysztof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8002920/
https://www.ncbi.nlm.nih.gov/pubmed/33803512
http://dx.doi.org/10.3390/cancers13061364