A Cell-Free Screen for Bacterial Membrane Disruptors Identifies Mefloquine as a Novel Antibiotic Adjuvant

Antibacterial discovery efforts have lagged far behind the need for new antibiotics. An approach that has gained popularity recently is targeting bacterial phospholipid membranes. We leveraged the differences between bacterial and mammalian phospholipid compositions to develop a high-throughput scre...

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Detalles Bibliográficos
Autores principales: Podoll, Jessica, Olson, Justin, Wang, Wei, Wang, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8002938/
https://www.ncbi.nlm.nih.gov/pubmed/33803571
http://dx.doi.org/10.3390/antibiotics10030315

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8002938/
https://www.ncbi.nlm.nih.gov/pubmed/33803571
http://dx.doi.org/10.3390/antibiotics10030315

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