Particle Forming Amorphous Solid Dispersions: A Mechanistic Randomized Pharmacokinetic Study in Humans

Amorphous solid dispersions (ASDs) are a promising drug-delivery strategy to overcome poor solubility through formulation. Currently, the understanding of drug absorption mechanisms from ASDs in humans is incomplete. Aiming to gain insights in this matter, we conducted a randomized cross-over design...

Descripción completa

Detalles Bibliográficos
Autores principales: Schittny, Andreas, Waldner, Samuel, Duthaler, Urs, Vorobyev, Alexander, Abramovich, Rimma, Krähenbühl, Stephan, Puchkov, Maxim, Huwyler, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003007/
https://www.ncbi.nlm.nih.gov/pubmed/33803049
http://dx.doi.org/10.3390/pharmaceutics13030401

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003007/
https://www.ncbi.nlm.nih.gov/pubmed/33803049
http://dx.doi.org/10.3390/pharmaceutics13030401

Ejemplares similares