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Particle Forming Amorphous Solid Dispersions: A Mechanistic Randomized Pharmacokinetic Study in Humans

Amorphous solid dispersions (ASDs) are a promising drug-delivery strategy to overcome poor solubility through formulation. Currently, the understanding of drug absorption mechanisms from ASDs in humans is incomplete. Aiming to gain insights in this matter, we conducted a randomized cross-over design...

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Detalles Bibliográficos
Autores principales:	Schittny, Andreas, Waldner, Samuel, Duthaler, Urs, Vorobyev, Alexander, Abramovich, Rimma, Krähenbühl, Stephan, Puchkov, Maxim, Huwyler, Jörg
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003007/ https://www.ncbi.nlm.nih.gov/pubmed/33803049 http://dx.doi.org/10.3390/pharmaceutics13030401

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