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Osteoblast-Derived Paracrine and Juxtacrine Signals Protect Disseminated Breast Cancer Cells from Stress

SIMPLE SUMMARY: Bone metastasis is a debilitating, incurable complication that occurs in breast cancer patients with a variable period of latency after treatment of the primary tumor. The seeding of individual cancer cells in the bone marrow from the primary tumor occurs early in disease progression...

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Detalles Bibliográficos
Autores principales: Hughes, Russell, Chen, Xinyue, Cowley, Natasha, Ottewell, Penelope D., Hawkins, Rhoda J., Hunter, Keith D., Hobbs, Jamie K., Brown, Nicola J., Holen, Ingunn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003019/
https://www.ncbi.nlm.nih.gov/pubmed/33803526
http://dx.doi.org/10.3390/cancers13061366