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Novel Ferrocene Derivatives Induce G0/G1 Cell Cycle Arrest and Apoptosis through the Mitochondrial Pathway in Human Hepatocellular Carcinoma

In this study, detailed information on hepatocellular carcinoma (HCC) cells (HepG-2, SMMC-7721, and HuH-7) and normal human liver cell L02 treated by ferrocene derivatives (compounds 1, 2 and 3) is provided. The cell viability assay showed that compound 1 presented the most potent and selective anti...

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Detalles Bibliográficos
Autores principales: Zheng, Jianrong, Zeng, Liao, Tang, Mingqing, Lin, Hongjun, Pi, Chao, Xu, Ruian, Cui, Xiuling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003055/
https://www.ncbi.nlm.nih.gov/pubmed/33803555
http://dx.doi.org/10.3390/ijms22063097