Design of Alphavirus Virus-Like Particles Presenting Circumsporozoite Junctional Epitopes That Elicit Protection against Malaria

The most advanced malaria vaccine, RTS,S, includes the central repeat and C-terminal domains of the Plasmodium falciparum circumsporozoite protein (PfCSP). We have recently isolated human antibodies that target the junctional region between the N-terminal and repeat domains that are not included in...

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Detalles Bibliográficos
Autores principales: Francica, Joseph R., Shi, Wei, Chuang, Gwo-Yu, Chen, Steven J., Da Silva Pereira, Lais, Farney, S. Katie, Flynn, Barbara J., Ou, Li, Stephens, Tyler, Tsybovsky, Yaroslav, Wang, Lawrence T., Anderson, Alexander, Beck, Zoltan, Dillon, Marlon, Idris, Azza H., Hurlburt, Nicholas, Liu, Tracy, Zhang, Baoshan, Alving, Carl R., Matyas, Gary R., Pancera, Marie, Mascola, John R., Kwong, Peter D., Seder, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003078/
https://www.ncbi.nlm.nih.gov/pubmed/33803622
http://dx.doi.org/10.3390/vaccines9030272

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003078/
https://www.ncbi.nlm.nih.gov/pubmed/33803622
http://dx.doi.org/10.3390/vaccines9030272

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