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Understanding the Potential Role of Sirtuin 2 on Aging: Consequences of SIRT2.3 Overexpression in Senescence

Sirtuin 2 (SIRT2) has been associated to aging and age-related pathologies. Specifically, an age-dependent accumulation of isoform 3 of SIRT2 in the CNS has been demonstrated; however, no study has addressed the behavioral or molecular consequences that this could have on aging. In the present study...

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Detalles Bibliográficos
Autores principales: Sola-Sevilla, Noemi, Ricobaraza, Ana, Hernandez-Alcoceba, Ruben, Aymerich, Maria S., Tordera, Rosa M., Puerta, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003096/
https://www.ncbi.nlm.nih.gov/pubmed/33803627
http://dx.doi.org/10.3390/ijms22063107