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Beta-1,3 Oligoglucans Specifically Bind to Immune Receptor CD28 and May Enhance T Cell Activation

Beta glucans are known to have immunomodulatory effects that mediated by a variety of mechanisms. In this article, we describe experiments and simulations suggesting that beta-1,3 glucans may promote activation of T cells by a previously unknown mechanism. First, we find that treatment of a T lympho...

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Detalles Bibliográficos
Autores principales: Comer, Jeffrey, Bassette, Molly, Burghart, Riley, Loyd, Mayme, Ishiguro, Susumu, Azhagiya Singam, Ettayapuram Ramaprasad, Vergara-Jaque, Ariela, Nakashima, Ayaka, Suzuki, Kengo, Geisbrecht, Brian V., Tamura, Masaaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003162/
https://www.ncbi.nlm.nih.gov/pubmed/33803858
http://dx.doi.org/10.3390/ijms22063124