A Novel Dipeptidyl Peptidase-4 Inhibitor DA-1229 Ameliorates Tubulointerstitial Fibrosis in Cyclosporine Nephrotoxicity in Mice

Cyclosporine A (CyA) is an immunosuppressive agent that induces nephrotoxicity with long-term treatment. The roles of DPP-4 and its inhibitors in cyclosporine nephrotoxicity are not fully understood. Therefore, we investigated the effects of a novel DPP-4 inhibitor, DA-1229, on the progression of re...

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Detalles Bibliográficos
Autores principales: Min, Hye Sook, Lee, Ji Eun, Ghee, Jung Yeon, Kang, Young Sun, Cha, Jin Joo, Han, Jee Young, Han, Sang Youb, Cha, Dae Ryong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003165/
https://www.ncbi.nlm.nih.gov/pubmed/33803842
http://dx.doi.org/10.3390/life11030251

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003165/
https://www.ncbi.nlm.nih.gov/pubmed/33803842
http://dx.doi.org/10.3390/life11030251

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