Identification of Genetic Modifiers of TDP-43: Inflammatory Activation of Astrocytes for Neuroinflammation

Transactive response DNA-binding protein 43 (TDP-43) is a ubiquitously expressed DNA/RNA-binding protein linked to amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). TDP-43 has been implicated in numerous aspects of the mRNA life cycle, as well as in cell toxicity and neuroinflam...

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Detalles Bibliográficos
Autores principales: Kim, Jae-Hong, Rahman, Md Habibur, Park, Donghwi, Jo, Myungjin, Kim, Hyung-Jun, Suk, Kyoungho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003223/
https://www.ncbi.nlm.nih.gov/pubmed/33803845
http://dx.doi.org/10.3390/cells10030676

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003223/
https://www.ncbi.nlm.nih.gov/pubmed/33803845
http://dx.doi.org/10.3390/cells10030676

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