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Identification of Genetic Modifiers of TDP-43: Inflammatory Activation of Astrocytes for Neuroinflammation

Transactive response DNA-binding protein 43 (TDP-43) is a ubiquitously expressed DNA/RNA-binding protein linked to amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). TDP-43 has been implicated in numerous aspects of the mRNA life cycle, as well as in cell toxicity and neuroinflam...

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Detalles Bibliográficos
Autores principales:	Kim, Jae-Hong, Rahman, Md Habibur, Park, Donghwi, Jo, Myungjin, Kim, Hyung-Jun, Suk, Kyoungho
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003223/ https://www.ncbi.nlm.nih.gov/pubmed/33803845 http://dx.doi.org/10.3390/cells10030676

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