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The Biological Significance of Targeting Acetylation-Mediated Gene Regulation for Designing New Mechanistic Tools and Potential Therapeutics

The molecular interplay between nucleosomal packaging and the chromatin landscape regulates the transcriptional programming and biological outcomes of downstream genes. An array of epigenetic modifications plays a pivotal role in shaping the chromatin architecture, which controls DNA access to the t...

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Detalles Bibliográficos
Autores principales: O’Garro, Chenise, Igbineweka, Loveth, Ali, Zonaira, Mezei, Mihaly, Mujtaba, Shiraz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003229/
https://www.ncbi.nlm.nih.gov/pubmed/33803759
http://dx.doi.org/10.3390/biom11030455