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Long-Term Caloric Restriction Attenuates β-Amyloid Neuropathology and Is Accompanied by Autophagy in APPswe/PS1delta9 Mice

Caloric restriction (CR) slows the aging process, extends lifespan, and exerts neuroprotective effects. It is widely accepted that CR attenuates β-amyloid (Aβ) neuropathology in models of Alzheimer’s disease (AD) by so-far unknown mechanisms. One promising process induced by CR is autophagy, which i...

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Detalles Bibliográficos
Autores principales: Müller, Luisa, Power Guerra, Nicole, Stenzel, Jan, Rühlmann, Claire, Lindner, Tobias, Krause, Bernd J., Vollmar, Brigitte, Teipel, Stefan, Kuhla, Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003277/
https://www.ncbi.nlm.nih.gov/pubmed/33803798
http://dx.doi.org/10.3390/nu13030985