Design and Synthesis of Ranitidine Analogs as Multi-Target Directed Ligands for the Treatment of Alzheimer’s Disease

The aggregation of amyloid β (Aβ) peptides and deposition of amyloid plaques are implicated in the pathogenesis of Alzheimer’s disease (AD). Therefore, blocking Aβ aggregation with small molecules has been proposed as one therapeutic approach for AD. In the present study, a series of ranitidine anal...

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Detalles Bibliográficos
Autores principales: Gao, Jie, Suo, Chen, Tseng, Jui-Heng, Moss, Melissa A., Terry, Alvin V., Chapman, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003314/
https://www.ncbi.nlm.nih.gov/pubmed/33803769
http://dx.doi.org/10.3390/ijms22063120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003314/
https://www.ncbi.nlm.nih.gov/pubmed/33803769
http://dx.doi.org/10.3390/ijms22063120

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