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Hypoxia-Driven Effects in Cancer: Characterization, Mechanisms, and Therapeutic Implications
Hypoxia, a common feature of solid tumors, greatly hinders the efficacy of conventional cancer treatments such as chemo-, radio-, and immunotherapy. The depletion of oxygen in proliferating and advanced tumors causes an array of genetic, transcriptional, and metabolic adaptations that promote surviv...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003323/ https://www.ncbi.nlm.nih.gov/pubmed/33808542 http://dx.doi.org/10.3390/cells10030678 |