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Hypoxia-Driven Effects in Cancer: Characterization, Mechanisms, and Therapeutic Implications

Hypoxia, a common feature of solid tumors, greatly hinders the efficacy of conventional cancer treatments such as chemo-, radio-, and immunotherapy. The depletion of oxygen in proliferating and advanced tumors causes an array of genetic, transcriptional, and metabolic adaptations that promote surviv...

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Detalles Bibliográficos
Autores principales:	Shi, Rachel, Liao, Chengheng, Zhang, Qing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003323/ https://www.ncbi.nlm.nih.gov/pubmed/33808542 http://dx.doi.org/10.3390/cells10030678

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