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Induction of AML Preleukemic Fusion Genes in HSPCs and DNA Damage Response in Preleukemic Fusion Gene Positive Samples

Preleukemic fusion genes (PFGs) occurring after DNA damage in hematopoietic stem progenitor cells (HSPCs) in utero often represent the initial event in the development of childhood leukemia. While the incidence of PFGs characteristic for acute lymphoblastic leukemia (ALL) was relatively well examine...

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Detalles Bibliográficos
Autores principales: Kosik, Pavol, Durdik, Matus, Skorvaga, Milan, Klimova, Daniela, Kochanova, Dominika, Cerna, Zlatica, Kubes, Miroslav, Holop, Marek, Belyaev, Igor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003332/
https://www.ncbi.nlm.nih.gov/pubmed/33803739
http://dx.doi.org/10.3390/antiox10030481