Species Differences in Microsomal Metabolism of Xanthine-Derived A(1) Adenosine Receptor Ligands

Tracer development for positron emission tomography (PET) requires thorough evaluation of pharmacokinetics, metabolism, and dosimetry of candidate radioligands in preclinical animal studies. Since variations in pharmacokinetics and metabolism of a compound occur in different species, careful selecti...

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Detalles Bibliográficos
Autores principales: Schneider, Daniela, Bier, Dirk, Holschbach, Marcus, Bauer, Andreas, Neumaier, Bernd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003343/
https://www.ncbi.nlm.nih.gov/pubmed/33803861
http://dx.doi.org/10.3390/ph14030277

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003343/
https://www.ncbi.nlm.nih.gov/pubmed/33803861
http://dx.doi.org/10.3390/ph14030277

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