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Metformin Attenuates Monosodium-Iodoacetate-Induced Osteoarthritis via Regulation of Pain Mediators and the Autophagy–Lysosomal Pathway

Osteoarthritis (OA) is the most common degenerative arthritis associated with pain and cartilage destruction in the elderly; it is known to be involved in inflammation as well. A drug called celecoxib is commonly used in patients with osteoarthritis to control pain. Metformin is used to treat type 2...

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Detalles Bibliográficos
Autores principales: Na, Hyun Sik, Kwon, Ji Ye, Lee, Seon-Yeong, Lee, Seung Hoon, Lee, A Ram, Woo, Jin Seok, Jung, KyungAh, Cho, Keun-Hyung, Choi, Jeong-Won, Lee, Dong Hwan, Min, Hong-Ki, Park, Sung-Hwan, Kim, Seok Jung, Cho, Mi-La
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003384/
https://www.ncbi.nlm.nih.gov/pubmed/33808727
http://dx.doi.org/10.3390/cells10030681