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Attribution of NF-κB Activity to CHUK/IKKα-Involved Carcinogenesis
SIMPLE SUMMARY: CHUK/IKKα has emerged as a novel tumor suppressor in several organs of humans and mice. In general, activation of NF-κB promotes inflammation and tumorigenesis. IKKα reduction stimulates inflammatory responses including NF-κB’s targets and NF-κB-independent pathways for tumor promoti...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003426/ https://www.ncbi.nlm.nih.gov/pubmed/33808757 http://dx.doi.org/10.3390/cancers13061411 |