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Attribution of NF-κB Activity to CHUK/IKKα-Involved Carcinogenesis

SIMPLE SUMMARY: CHUK/IKKα has emerged as a novel tumor suppressor in several organs of humans and mice. In general, activation of NF-κB promotes inflammation and tumorigenesis. IKKα reduction stimulates inflammatory responses including NF-κB’s targets and NF-κB-independent pathways for tumor promoti...

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Detalles Bibliográficos
Autores principales: Li, Xin, Hu, Yinling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003426/
https://www.ncbi.nlm.nih.gov/pubmed/33808757
http://dx.doi.org/10.3390/cancers13061411