CD19 Chimeric Antigen Receptor-Exosome Targets CD19 Positive B-lineage Acute Lymphocytic Leukemia and Induces Cytotoxicity

SIMPLE SUMMARY: Our research describes our designer exosomes express CD19 Chimeric Antigen Receptor (Exo-CD19 CAR). This novel Exo-CD19 CAR is cytotoxic for CD19-positive leukemia B-cells without interfering with cytotoxicity in CD19-negative cells. This innovation can be translated into broader cli...

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Detalles Bibliográficos
Autores principales: Haque, Shabirul, Vaiselbuh, Sarah R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003442/
https://www.ncbi.nlm.nih.gov/pubmed/33808645
http://dx.doi.org/10.3390/cancers13061401

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003442/
https://www.ncbi.nlm.nih.gov/pubmed/33808645
http://dx.doi.org/10.3390/cancers13061401

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