Immunization with Epstein–Barr Virus Core Fusion Machinery Envelope Proteins Elicit High Titers of Neutralizing Activities and Protect Humanized Mice from Lethal Dose EBV Challenge

Epstein–Barr virus (EBV) is the primary cause of infectious mononucleosis and is strongly implicated in the etiology of multiple lymphoid and epithelial cancers. EBV core fusion machinery envelope proteins gH/gL and gB coordinately mediate EBV fusion and entry into its target cells, B lymphocytes an...

Descripción completa

Detalles Bibliográficos
Autores principales: Cui, Xinle, Cao, Zhouhong, Ishikawa, Yuriko, Cui, Sara, Imadome, Ken-Ichi, Snapper, Clifford M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003492/
https://www.ncbi.nlm.nih.gov/pubmed/33808755
http://dx.doi.org/10.3390/vaccines9030285

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003492/
https://www.ncbi.nlm.nih.gov/pubmed/33808755
http://dx.doi.org/10.3390/vaccines9030285

Ejemplares similares