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Immunization with Epstein–Barr Virus Core Fusion Machinery Envelope Proteins Elicit High Titers of Neutralizing Activities and Protect Humanized Mice from Lethal Dose EBV Challenge
Epstein–Barr virus (EBV) is the primary cause of infectious mononucleosis and is strongly implicated in the etiology of multiple lymphoid and epithelial cancers. EBV core fusion machinery envelope proteins gH/gL and gB coordinately mediate EBV fusion and entry into its target cells, B lymphocytes an...
Autores principales: | Cui, Xinle, Cao, Zhouhong, Ishikawa, Yuriko, Cui, Sara, Imadome, Ken-Ichi, Snapper, Clifford M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003492/ https://www.ncbi.nlm.nih.gov/pubmed/33808755 http://dx.doi.org/10.3390/vaccines9030285 |
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