A MAPK/miR-29 Axis Suppresses Melanoma by Targeting MAFG and MYBL2

SIMPLE SUMMARY: The miR-29 family is subjected to complex regulation by tumor suppressors and oncogenes and has tumor suppressive potential in several cancers. We demonstrate that, in melanoma, oncogenic BRAF paradoxically induces miR-29 in concert with p53, thereby forming a barrier to melanoma pro...

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Detalles Bibliográficos
Autores principales: Vera, Olga, Bok, Ilah, Jasani, Neel, Nakamura, Koji, Xu, Xiaonan, Mecozzi, Nicol, Angarita, Ariana, Wang, Kaizhen, Tsai, Kenneth Y., Karreth, Florian A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003541/
https://www.ncbi.nlm.nih.gov/pubmed/33808771
http://dx.doi.org/10.3390/cancers13061408

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003541/
https://www.ncbi.nlm.nih.gov/pubmed/33808771
http://dx.doi.org/10.3390/cancers13061408

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