Genomic, Transcriptomic, and Functional Alterations in DNA Damage Response Pathways as Putative Biomarkers of Chemotherapy Response in Ovarian Cancer

SIMPLE SUMMARY: Several chemotherapy drugs are approved for ovarian cancer treatment in the neo-adjuvant/adjuvant setting as well as following relapse. These include carboplatin, paclitaxel, doxorubicin, topotecan, PARP inhibitors (PARPi), and gemcitabine. However, except for PAPRi, there are no pre...

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Detalles Bibliográficos
Autores principales: Sharma Saha, Sweta, Gentles, Lucy, Bradbury, Alice, Brecht, Dominik, Robinson, Rebecca, O’Donnell, Rachel, Curtin, Nicola J., Drew, Yvette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003626/
https://www.ncbi.nlm.nih.gov/pubmed/33804647
http://dx.doi.org/10.3390/cancers13061420

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003626/
https://www.ncbi.nlm.nih.gov/pubmed/33804647
http://dx.doi.org/10.3390/cancers13061420

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