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Members of the Fibroblast Growth Factor Receptor Superfamily Are Proteolytically Cleaved by Two Differently Activated Metalloproteases

Fibroblast growth factor receptors (FGFRs) are a family of receptor tyrosine kinases that have been associated not only with various cellular processes, such as embryonic development and adult wound healing but also enhanced tumor survival, angiogenesis, and metastatic spread. Proteolytic cleavage o...

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Detalles Bibliográficos
Autores principales: Dixit, Garima, Schanz, Willow, Pappas, Benjamin A., Maretzky, Thorsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003738/
https://www.ncbi.nlm.nih.gov/pubmed/33804608
http://dx.doi.org/10.3390/ijms22063165