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Towards Enhanced MRI Performance of Tumor-Specific Dimeric Phenylboronic Contrast Agents

It is known that phenylboronic acid (PBA) can target tumor tissues by binding to sialic acid, a substrate overexpressed by cancer cells. This capability has previously been explored in the design of targeting diagnostic probes such as Gd- and (68)Ga-DOTA-EN-PBA, two contrast agents for magnetic reso...

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Detalles Bibliográficos
Autores principales: Martinelli, Jonathan, Tei, Lorenzo, Geninatti Crich, Simonetta, Alberti, Diego, Djanashvili, Kristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003780/
https://www.ncbi.nlm.nih.gov/pubmed/33808910
http://dx.doi.org/10.3390/molecules26061730