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An Improved Synthesis of N-(4-[(18)F]Fluorobenzoyl)-Interleukin-2 for the Preclinical PET Imaging of Tumour-Infiltrating T-cells in CT26 and MC38 Colon Cancer Models

Positron emission tomography (PET) imaging of activated T-cells with N-(4-[(18)F]fluorobenzoyl)-interleukin-2 ([(18)F]FB-IL-2) may be a promising tool for patient management to aid in the assessment of clinical responses to immune therapeutics. Unfortunately, existing radiosynthetic methods are very...

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Detalles Bibliográficos
Autores principales: Khanapur, Shivashankar, Yong, Fui Fong, Hartimath, Siddesh V., Jiang, Lingfan, Ramasamy, Boominathan, Cheng, Peter, Narayanaswamy, Pradeep, Goggi, Julian L., Robins, Edward George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003786/
https://www.ncbi.nlm.nih.gov/pubmed/33808813
http://dx.doi.org/10.3390/molecules26061728