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FLT3-ITD Allelic Burden and Acute Promyelocytic Leukemia Risk Stratification

SIMPLE SUMMARY: Around 12–38% of acute promyelocytic leukemia (APL) patients carry the FLT3-ITD mutation, which has been associated with several poor-prognosis indicators such as high white blood cell counts, M3v variant morphology, and the bcr3 isoform. We aimed to retrospectively study the impact...

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Detalles Bibliográficos
Autores principales: Li, Andrew Y., Kashanian, Sarah M., Hambley, Bryan C., Zacholski, Kyle, Duong, Vu H., El Chaer, Firas, Holtzman, Noa G., Gojo, Ivana, Webster, Jonathan A., Norsworthy, Kelly J., Smith, Bruce Douglas, DeZern, Amy E., Levis, Mark J., Baer, Maria R., Kamangar, Farin, Ghiaur, Gabriel, Emadi, Ashkan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003857/
https://www.ncbi.nlm.nih.gov/pubmed/33800974
http://dx.doi.org/10.3390/biology10030243