Genetic Correction of IL-10RB Deficiency Reconstitutes Anti-Inflammatory Regulation in iPSC-Derived Macrophages

Patient material from rare diseases such as very early-onset inflammatory bowel disease (VEO-IBD) is often limited. The use of patient-derived induced pluripotent stem cells (iPSCs) for disease modeling is a promising approach to investigate disease pathomechanisms and therapeutic strategies. We suc...

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Detalles Bibliográficos
Autores principales: Hoffmann, Dirk, Sens, Johanna, Brennig, Sebastian, Brand, Daniel, Philipp, Friederike, Vollmer Barbosa, Philippe, Kuehle, Johannes, Steinemann, Doris, Lenz, Daniela, Buchegger, Theresa, Morgan, Michael, Falk, Christine S., Klein, Christoph, Lachmann, Nico, Schambach, Axel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003874/
https://www.ncbi.nlm.nih.gov/pubmed/33804706
http://dx.doi.org/10.3390/jpm11030221

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003874/
https://www.ncbi.nlm.nih.gov/pubmed/33804706
http://dx.doi.org/10.3390/jpm11030221

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