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Polymeric Nanovectors Incorporated with Ganciclovir and HSV-tk Encoding Plasmid for Gene-Directed Enzyme Prodrug Therapy

In the area of gene-directed enzyme prodrug therapy (GDEPT), using herpes simplex virus thymidine kinase (HSV-tk) paired with prodrug ganciclovir (GCV) for cancer treatment has been extensively studied. It is a process involved with two steps whereby the gene (HSV-tk) is first delivered to malignant...

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Detalles Bibliográficos
Autores principales: Sawdon, Alicia J., Zhang, Jun, Peng, Sarah, Alyami, Esmael M., Peng, Ching-An
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003905/
https://www.ncbi.nlm.nih.gov/pubmed/33801024
http://dx.doi.org/10.3390/molecules26061759