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Cannabinoid Quinones—A Review and Novel Observations

A cannabinoid anticancer para-quinone, HU-331, which was synthesized by our group five decades ago, was shown to have very high efficacy against human cancer cell lines in-vitro and against in-vivo grafts of human tumors in nude mice. The main mechanism was topoisomerase IIα catalytic inhibition. La...

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Detalles Bibliográficos
Autores principales: Kogan, Natalya M., Peters, Maximilian, Mechoulam, Raphael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8003933/
https://www.ncbi.nlm.nih.gov/pubmed/33801057
http://dx.doi.org/10.3390/molecules26061761