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Embryonic-Derived Myb(−) Macrophages Enhance Bacterial Clearance and Improve Survival in Rat Sepsis

Peritoneal resident macrophages play a key role in combating sepsis in the peritoneal cavity. We sought to determine if peritoneal transplantation of embryonic Myb(−) “peritoneal-like” macrophages attenuate abdominal fecal sepsis. Directed differentiation of rodent pluripotent stem cells (PSCs) was...

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Detalles Bibliográficos
Autores principales: Jerkic, Mirjana, Litvack, Michael L., Gagnon, Stéphane, Otulakowski, Gail, Zhang, Haibo, Rotstein, Ori, Kavanagh, Brian P., Post, Martin, Laffey, John G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8004006/
https://www.ncbi.nlm.nih.gov/pubmed/33804806
http://dx.doi.org/10.3390/ijms22063190