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Multiparticulate Systems of Ezetimibe Micellar System and Atorvastatin Solid Dispersion Efficacy of Low-Dose Ezetimibe/Atorvastatin on High-Fat Diet-Induced Hyperlipidemia and Hepatic Steatosis in Diabetic Rats

The aim of this study was to develop multiparticulate systems with a combination of ezetimibe micellar systems and atorvastatin solid dispersions using croscarmellose as a hydrophilic vehicle and Kolliphor RH40 as a surfactant. The presence of a surfactant with low hydrophilic polymer ratios produce...

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Detalles Bibliográficos
Autores principales: Torrado-Salmerón, Carlos, Guarnizo-Herrero, Víctor, Henriques, Joana, Seiça, Raquel, Sena, Cristina M., Torrado-Santiago, Santiago
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8004026/
https://www.ncbi.nlm.nih.gov/pubmed/33804727
http://dx.doi.org/10.3390/pharmaceutics13030421