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Selective dendritic localization of mRNA in Drosophila mushroom body output neurons

Memory-relevant neuronal plasticity is believed to require local translation of new proteins at synapses. Understanding this process requires the visualization of the relevant mRNAs within these neuronal compartments. Here, we used single-molecule fluorescence in situ hybridization to localize mRNAs...

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Detalles Bibliográficos
Autores principales: Mitchell, Jessica, Smith, Carlas S, Titlow, Josh, Otto, Nils, van Velde, Pieter, Booth, Martin, Davis, Ilan, Waddell, Scott
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8004107/
https://www.ncbi.nlm.nih.gov/pubmed/33724180
http://dx.doi.org/10.7554/eLife.62770