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Computational Modeling to Explain Why 5,5-Diarylpentadienamides are TRPV1 Antagonists

Several years ago, the crystallographic structures of the transient receptor potential vanilloid 1 (TRPV1) in the presence of agonists and antagonists were reported, providing structural information about its chemical activation and inactivation. TRPV1’s activation increases the transport of calcium...

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Detalles Bibliográficos
Autor principal: Caballero, Julio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8004144/
https://www.ncbi.nlm.nih.gov/pubmed/33801115
http://dx.doi.org/10.3390/molecules26061765