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Computational Modeling to Explain Why 5,5-Diarylpentadienamides are TRPV1 Antagonists
Several years ago, the crystallographic structures of the transient receptor potential vanilloid 1 (TRPV1) in the presence of agonists and antagonists were reported, providing structural information about its chemical activation and inactivation. TRPV1’s activation increases the transport of calcium...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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MDPI
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8004144/ https://www.ncbi.nlm.nih.gov/pubmed/33801115 http://dx.doi.org/10.3390/molecules26061765 |