Stable Isotopic Tracer Phospholipidomics Reveals Contributions of Key Phospholipid Biosynthetic Pathways to Low Hepatocyte Phosphatidylcholine to Phosphatidylethanolamine Ratio Induced by Free Fatty Acids

There is a strong association between hepatocyte phospholipid homeostasis and non-alcoholic fatty liver disease (NAFLD). The phosphatidylcholine to phosphatidylethanolamine ratio (PC/PE) often draws special attention as genetic and dietary disruptions to this ratio can provoke steatohepatitis and ot...

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Detalles Bibliográficos
Autores principales: Peng, Kang-Yu, Barlow, Christopher K, Kammoun, Helene, Mellett, Natalie A, Weir, Jacquelyn M, Murphy, Andrew J, Febbraio, Mark A, Meikle, Peter J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8004269/
https://www.ncbi.nlm.nih.gov/pubmed/33809964
http://dx.doi.org/10.3390/metabo11030188

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8004269/
https://www.ncbi.nlm.nih.gov/pubmed/33809964
http://dx.doi.org/10.3390/metabo11030188

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