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Stable Isotopic Tracer Phospholipidomics Reveals Contributions of Key Phospholipid Biosynthetic Pathways to Low Hepatocyte Phosphatidylcholine to Phosphatidylethanolamine Ratio Induced by Free Fatty Acids
There is a strong association between hepatocyte phospholipid homeostasis and non-alcoholic fatty liver disease (NAFLD). The phosphatidylcholine to phosphatidylethanolamine ratio (PC/PE) often draws special attention as genetic and dietary disruptions to this ratio can provoke steatohepatitis and ot...
Autores principales: | Peng, Kang-Yu, Barlow, Christopher K, Kammoun, Helene, Mellett, Natalie A, Weir, Jacquelyn M, Murphy, Andrew J, Febbraio, Mark A, Meikle, Peter J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8004269/ https://www.ncbi.nlm.nih.gov/pubmed/33809964 http://dx.doi.org/10.3390/metabo11030188 |
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