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Is there a renoprotective value to leukodepletion during heart valve surgery? A randomized controlled trial (ROLO)

BACKGROUND: Acute Kidney Injury (AKI) adversely affects outcomes after cardiac surgery. A major mediator of AKI is the activation of leukocytes through exposure to the cardiopulmonary bypass circuit. We evaluate the use of leukodepletion filters throughout bypass to protect against post-operative AK...

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Detalles Bibliográficos
Autores principales: Khoshbin, Espeed, Spencer, Sally, Solomon, Laurence, Tang, Augustine, Clark, Stephen, Stokes, Elizabeth, Wordsworth, Sarah, Dabner, Lucy, Edwards, Julia, Reeves, Barnaby, Rogers, Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8004389/
https://www.ncbi.nlm.nih.gov/pubmed/33771192
http://dx.doi.org/10.1186/s13019-021-01402-4