Microglial PGC-1α protects against ischemic brain injury by suppressing neuroinflammation

BACKGROUND: Neuroinflammation and immune responses occurring minutes to hours after stroke are associated with brain injury after acute ischemic stroke (AIS). PPARγ coactivator-1α (PGC-1α), as a master coregulator of gene expression in mitochondrial biogenesis, was found to be transiently upregulate...

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Detalles Bibliográficos
Autores principales: Han, Bin, Jiang, Wei, Cui, Pan, Zheng, Kai, Dang, Chun, Wang, Junjie, Li, He, Chen, Lin, Zhang, Rongxin, Wang, Qing Mei, Ju, Zhenyu, Hao, Junwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8004413/
https://www.ncbi.nlm.nih.gov/pubmed/33771213
http://dx.doi.org/10.1186/s13073-021-00863-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8004413/
https://www.ncbi.nlm.nih.gov/pubmed/33771213
http://dx.doi.org/10.1186/s13073-021-00863-5

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