Optimal empiric treatment for KPC-2-producing Klebsiella pneumoniae infections in critically ill patients with normal or decreased renal function using Monte Carlo simulation

BACKGROUND: Limited clinical studies describe the pharmacodynamics of fosfomycin (FOS), tigecycline (TGC) and colistin methanesulfonate (CMS) in combination against KPC-producing Klebsiella pneumoniae (KPC-Kp). Population pharmacokinetic models were used in our study. Monte Carlo simulation was cond...

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Detalles Bibliográficos
Autores principales: Wang, Guoan, Yu, Wei, Cui, Yushan, Shi, Qingyi, Huang, Chen, Xiao, Yonghong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8004468/
https://www.ncbi.nlm.nih.gov/pubmed/33771113
http://dx.doi.org/10.1186/s12879-021-06000-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8004468/
https://www.ncbi.nlm.nih.gov/pubmed/33771113
http://dx.doi.org/10.1186/s12879-021-06000-2

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