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The anxiety and ethanol intake controlling GAL5.1 enhancer is epigenetically modulated by, and controls preference for, high-fat diet

Excess maternal fat intake and obesity increase offspring susceptibility to conditions such as chronic anxiety and substance abuse. We hypothesised that environmentally modulated DNA methylation changes (5mC/5hmC) in regulatory regions of the genome that modulate mood and consumptive behaviours coul...

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Detalles Bibliográficos
Autores principales: McEwan, Andrew, Erickson, Johanna Celene, Davidson, Connor, Heijkoop, Jenny, Turnbull, Yvonne, Delibegovic, Mirela, Murgatroyd, Christopher, MacKenzie, Alasdair
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8004485/
https://www.ncbi.nlm.nih.gov/pubmed/33313982
http://dx.doi.org/10.1007/s00018-020-03705-6