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Cell signaling pathways in autosomal-dominant leukodystrophy (ADLD): the intriguing role of the astrocytes

Autosomal-dominant leukodystrophy (ADLD) is a rare fatal neurodegenerative disorder with overexpression of the nuclear lamina component, Lamin B1 due to LMNB1 gene duplication or deletions upstream of the gene. The molecular mechanisms responsible for driving the onset and development of this pathol...

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Detalles Bibliográficos
Autores principales: Ratti, Stefano, Rusciano, Isabella, Mongiorgi, Sara, Owusu Obeng, Eric, Cappellini, Alessandra, Teti, Gabriella, Falconi, Mirella, Talozzi, Lia, Capellari, Sabina, Bartoletti-Stella, Anna, Guaraldi, Pietro, Cortelli, Pietro, Suh, Pann-Ghill, Cocco, Lucio, Manzoli, Lucia, Ramazzotti, Giulia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8004488/
https://www.ncbi.nlm.nih.gov/pubmed/33034697
http://dx.doi.org/10.1007/s00018-020-03661-1