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Cell signaling pathways in autosomal-dominant leukodystrophy (ADLD): the intriguing role of the astrocytes
Autosomal-dominant leukodystrophy (ADLD) is a rare fatal neurodegenerative disorder with overexpression of the nuclear lamina component, Lamin B1 due to LMNB1 gene duplication or deletions upstream of the gene. The molecular mechanisms responsible for driving the onset and development of this pathol...
Autores principales: | Ratti, Stefano, Rusciano, Isabella, Mongiorgi, Sara, Owusu Obeng, Eric, Cappellini, Alessandra, Teti, Gabriella, Falconi, Mirella, Talozzi, Lia, Capellari, Sabina, Bartoletti-Stella, Anna, Guaraldi, Pietro, Cortelli, Pietro, Suh, Pann-Ghill, Cocco, Lucio, Manzoli, Lucia, Ramazzotti, Giulia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8004488/ https://www.ncbi.nlm.nih.gov/pubmed/33034697 http://dx.doi.org/10.1007/s00018-020-03661-1 |
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