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Human RNase3 immune modulation by catalytic-dependent and independent modes in a macrophage-cell line infection model
The human RNase3 is a member of the RNaseA superfamily involved in host immunity. RNase3 is expressed by leukocytes and shows broad-spectrum antimicrobial activity. Together with a direct antimicrobial action, RNase3 exhibits immunomodulatory properties. Here, we have analysed the transcriptome of m...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8004517/ https://www.ncbi.nlm.nih.gov/pubmed/33226440 http://dx.doi.org/10.1007/s00018-020-03695-5 |