Targeting CX3CR1 Suppresses the Fanconi Anemia DNA Repair Pathway and Synergizes with Platinum

SIMPLE SUMMARY: Chemotherapeutics exerting their antiproliferative actions by introducing DNA crosslinks, such as platinum drugs, are used to treat numerous cancers. Unfortunately, their therapeutic potential is limited due to adverse side effects and acquired resistance, the latter often associated...

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Detalles Bibliográficos
Autores principales: Lehto, Jemina, Huguet Ninou, Anna, Chioureas, Dimitrios, Jonkers, Jos, Gustafsson, Nina M. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8004634/
https://www.ncbi.nlm.nih.gov/pubmed/33810010
http://dx.doi.org/10.3390/cancers13061442

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8004634/
https://www.ncbi.nlm.nih.gov/pubmed/33810010
http://dx.doi.org/10.3390/cancers13061442

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